From the number one pediatrician-recommended lice removal brand.* Nix Creme Rinse will kill head lice and eggs (nits) for kids or adults through the use of permethrin, an insecticide that kills lice. First, apply Nix Creme Rinse to head hair to kill lice and eggs (nits). Next, remove lice and eggs (nits) from head hair with the Nix Nit Comb. Nix Creme Rinse is for use on head hair and is safe for use on children 2 months and older. It prevents reinfestation for up to 14 days after the initial application. Nix lice treatment is trusted by parents and feared by lice. Nix offers a variety of lice combs, shampoos, treatment kits, hair prevention spray and lice spray for furniture and bedding to nix out lice in your home. *Based on Pediatrician Survey December 6, 2022